PLoS Medicine, 15 December 2015 Summary Points Health disparities persist across race/ethnicity for the majority of Healthy People 2010 health indicators. Most physicians and scientists are informed by research extrapolated from a largely homogenous population, usually white and male. A growing proportion of Americans are not fully benefiting from clinical and biomedical advances since racial and ethnic […]
U.S. Food and Drug Administration, 9 December 2015 Have you ever wondered if someone like you participated in the clinical trials for a new drug? If you have, you’re not alone. That’s why FDA is making demographic information from clinical trials, such as the inclusion of women and minority groups, more easily available to consumers through its […]
Media Planet: Future of Health Care, December 2015 Historically, participants in clinical trials have not proportionally represented the diversity of our population. This is a stat we can set about changing today. Read more.
A literature review on the representativeness of randomized controlled trial samples and implications for the external validity of trial results
Trials, 3 Novmber 2015 Randomized controlled trials (RCTs) are conducted under idealized and rigorously controlled conditions that may compromise their external validity. A literature review was conducted of published English language articles that reported the findings of studies assessing external validity by a comparison of the patient sample included in RCTs reporting on pharmaceutical interventions with patients […]
The Catalyst, 15 October 2015 Clinical trials involve many different people and institutions coming together to better understand disease, biology and the impact of potential medicines. Carefully conducted clinical trials are the fastest and safest way to find treatments that work in people and improve public health. But they are more than a process—it takes a dynamic […]
FDA: 8/5/14 What is clinical research? Clinical research refers to studies in which people participate as patients or volunteers. Different terms are used to describe clinical research, including: clinical studies clinical trials studies research trials protocols. Clinical research may have a number of goals, such as: developing new treatments or medications identifying causes of illness studying […]
FDA: 7/31/14 Personalized medicine is an evolving field of medicine in which treatments are tailored to the individual patient. You may have a condition, for example, that is caused by a mutation in your genes. With advances in personalized medicine, you might be prescribed a medication that targets that specific mutation. To learn which patients […]